Custom Peptides
Cayman Chemical SGC2085hydrochlorIde 10mg
A P2Y12 receptor antagonist inhibits collagen- arachidonic acid- and ADP-induced aggregation of human platelets (IC50s 75 600 and 1300 M respectively) inhibits ADP-induced aggregation of rat platelets decreases thrombus weight in a rat model of arterio-venous shunt thrombosis at 100 mg/kg inhibits healing of acetic acid-induced gastric ulcers in rats at 300 mg/kg
Cayman Chemical 14-nhydrodIgItoxIgenIn 10mg
A triacylglycerol has been found in palm and vegetable oils
Cayman Chemical Cebrnopadol 10mg
A long-chain atypical ceramide containing a 1-deoxysphingosine (m181(4E)) backbone
Cayman Chemical trmentIc AcId 10mg
A triacylglycerol has been found in human milk butterfat and palm kernel oil
Cayman Chemical CInserInhydrochlorIde 10mg
An orally bioavailable inhibitor of ASK1 (IC50 14 nM) selective for ASK1 over ASK2 (IC50 510 nM) as well as MEKK1 TAK-1 IKKB ERK1 JNK1 p38a GSK3B PKC and B-RAF (IC50s 10000 nM for all) inhibits streptozotocin-induced increases in JNK and p38 phosphorylation in INS-1 pancreatic B cells in a concentration-dependent manner
Cayman Chemical 1 2 3TrIoctnoyl GlycRol13 10mg
A Smoothened receptor antagonist binds to human recombinant Smo expressed in HEK293T cells (IC50 1 1 UM) inhibits Gli1-mediated hedgehog signaling in a reporter assay (IC50 1 5 UM) an inhibitor of 11b-hydroxy steroid dehydrogenase-1 reduces tumor growth in a murine medulloblastoma mouse allograft model at 40 and 80 mg/kg per day) induces tumor regression at 80 mg/kg twice per day reduces expression of the hedgehog pathway-associated transcription factor Gli1 in tumor tissue
Cayman Chemical NIsoxetInhydrochlorIde 10mg
A flavonoid glycoside has a relative antioxidant capacity of 1 45 compared to Trolox in an ABTS assay inhibits lipid peroxidation in a cell-free assay using phospholipid liposomes (IC50 9 2 M)
Cayman Chemical Longspur epmdum Epmedn B 10mg
A fluoroquinolone antibiotic active against isolates of anaerobic bacteria including B fragilis as well as Fusobacterium and Actinomyces species (MICs 0 125- 8 Ug/ml) eliminates E coli and B fragilis infection in a rat intra-abdominal abscess model at 40 mg/kg three times per day
Cayman Chemical ImetIthydrobromIde 10mg
An analytical reference standard categorized as a prodrug form of Y-hydroxyvaleric acid intended for research and forensic applications
Cayman Chemical 3 3-2-Chlorophenylmethyle 10mg
An inhibitor of Mer kinase (IC50 4 3 nM) selective for Mer over Axl and TYRO3 (IC50s 360 and 250 nM respectively) inhibits phosphorylation of Mer in 697 B-ALL cells (IC50 21 9 nM) inhibits platelet aggregation and ATP release induced by type I equine fibrillar collagen in isolated human platelet-rich plasma at 3 M
Cayman Chemical 2 5DIhydroxycInaMC ACD ph 10mg
An ansa macrolide inhibits polymerization and induces depolymerization of bovine brain tubulin (EC50s 12 and 43 UM respectively) inhibits sea urchin egg mitosis at 10 UM and decreases proliferation of KB nasopharyngeal cancer cells (EC50 0 19 Ug/ml)
Cayman Chemical 21hydroxy HenIcosnoIc ACD 10mg
Immunogen Human recombinant protein Host Rabbit Species Reactivity ( ) Human asprosin Applications IP WB